Lithium Bromide → 2-Ethylidene-2',3'-dichloro4'-methoxypropiophenone
Reaction equation
Br[C:2]([CH3:17])([CH2:15][CH3:16])[C:3]([C:5]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[C:7]([Cl:13])[C:6]=1[Cl:14])=[O:4].[Br-].[Li+]>CN(C=O)C>[CH:15](=[C:2]([CH3:17])[C:3]([C:5]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[C:7]([Cl:13])[C:6]=1[Cl:14])=[O:4])[CH3:16]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
By following the procedure described in Example 5, Step C, using as the reactants 2-bromo-2-methyl-2',3'-dichloro-4'-methoxybutyrophenone (34 g., 0.1 mole), lithium bromide (17.4 g., 0.2 mole) and DMF (200 ml.), there is obtained 2-ethylidene-2',3'-dichloro-4'-methoxypropiophenone.
Sources & evidence
- ORD record
- ord-f8ad71e647ea498194c4c9cb6317fbdb
- Source dataset
- uspto-grants-1978_04
- Patent number
- US04085219
Reaction notes
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