Hydrochloric Acid → 6-Methyl-5-[4-(2-furoyl)piperazin-1-ylmethyl]-4-(3-nitrophenyl)-2-phenylpyrimidine

HRID 208628

Reaction equation

HRID 208628 reaction equation
[CH3:3][c:4]1[c:5]([CH2:25][N:26]2[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]2)[c:6](-[c:16]2[cH:17][c:18]([N+:22](=[O:23])[O-:24])[cH:19][cH:20][cH:21]2)[n:7][c:8](-[c:10]2[cH:11][cH:12][cH:13][cH:14][cH:15]2)[n:9]1.[CH3:43][CH2:44][N:45]([CH2:46][CH3:47])[CH2:48][CH3:49].[Cl:32][CH2:33][Cl:34].[ClH:1].[ClH:2].[o:35]1[c:36]([C:40](=[O:41])[Cl:42])[cH:37][cH:38][cH:39]1>>[CH3:3][c:4]1[c:5]([CH2:25][N:26]2[CH2:27][CH2:28][N:29]([C:40]([c:36]3[o:35][cH:39][cH:38][cH:37]3)=[O:41])[CH2:30][CH2:31]2)[c:6](-[c:16]2[cH:17][c:18]([N+:22](=[O:23])[O-:24])[cH:19][cH:20][cH:21]2)[n:7][c:8](-[c:10]2[cH:11][cH:12][cH:13][cH:14][cH:15]2)[n:9]1

Participants

6

Reactant 5

HCID 313Hydrochloric Acid2×HCID 6344DichloromethaneHCID 8471TriethylamineHCID 682422-Furancarbonyl chlorideHCID 100232404-Methyl-6-(3-nitrophenyl)-2-phenyl-5-(piperazin-1-ylmethyl)pyrimidine

Product 1

HCID 201514026-Methyl-5-[4-(2-furoyl)piperazin-1-ylmethyl]-4-(3-nitrophenyl)-2-phenylpyrimidine

Sources & evidence

ORD record
ord-268c19b1c5da414dbab72bcd979be8dc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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