Dimethylformamide → 6-Chloro-2-methyl-3-nitropyridin-4-amine

HRID 210346

Reaction equation

HRID 210346 reaction equation
[CH3:13][Al:14]([CH3:15])[CH3:16].[Cl:1][c:2]1[n:3][c:4]([Cl:12])[cH:5][c:6]([NH2:11])[c:7]1[N+:8](=[O:9])[O-:10].[O:17]=[CH:18][N:19]([CH3:20])[CH3:21].[cH:22]1[cH:23][cH:24][c:25]([P:26]([Pd:27]([P:28]([c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)([c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[c:41]2[cH:42][cH:43][cH:44][cH:45][cH:46]2)([P:47]([c:48]2[cH:49][cH:50][cH:51][cH:52][cH:53]2)([c:54]2[cH:55][cH:56][cH:57][cH:58][cH:59]2)[c:60]2[cH:61][cH:62][cH:63][cH:64][cH:65]2)[P:66]([c:67]2[cH:68][cH:69][cH:70][cH:71][cH:72]2)([c:73]2[cH:74][cH:75][cH:76][cH:77][cH:78]2)[c:79]2[cH:80][cH:81][cH:82][cH:83][cH:84]2)([c:85]2[cH:86][cH:87][cH:88][cH:89][cH:90]2)[c:91]2[cH:92][cH:93][cH:94][cH:95][cH:96]2)[cH:97][cH:98]1>>[c:2]1([CH3:13])[n:3][c:4]([Cl:12])[cH:5][c:6]([NH2:11])[c:7]1[N+:8](=[O:9])[O-:10]

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 2827402,6-Dichloro-3-nitropyridin-4-amineHCID 16682925TrimethylaluminumHCID 178420554HCID 178420554, compound

Product 1

HCID 184399466-Chloro-2-methyl-3-nitropyridin-4-amine

Sources & evidence

ORD record
ord-9dab0d9b78cd4688a91036f2826a24a9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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