Propargyl bromide → 1-[3-({4-Amino-7-[3-(1-piperidinyl)-1-propyn-1-yl]pyrrolo[2,1-f][1,2,4]triazin-5-yl}carbonyl)phenyl]-3-(2,4-dichlorophenyl)urea
Reaction equation
[NH:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH2:7](Br)[C:8]#[CH:9].[NH2:11][C:12]1[C:17]2=[C:18]([C:22]([C:24]3[CH:25]=[C:26]([NH:30][C:31]([NH:33][C:34]4[CH:39]=[CH:38][C:37]([Cl:40])=[CH:36][C:35]=4[Cl:41])=[O:32])[CH:27]=[CH:28][CH:29]=3)=[O:23])[CH:19]=[C:20](Br)[N:16]2[N:15]=[CH:14][N:13]=1>[Cu]I.Cl[Pd](Cl)([P](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)[P](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1>[NH2:11][C:12]1[C:17]2=[C:18]([C:22]([C:24]3[CH:25]=[C:26]([NH:30][C:31]([NH:33][C:34]4[CH:39]=[CH:38][C:37]([Cl:40])=[CH:36][C:35]=4[Cl:41])=[O:32])[CH:27]=[CH:28][CH:29]=3)=[O:23])[CH:19]=[C:20]([C:7]#[C:8][CH2:9][N:1]3[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]3)[N:16]2[N:15]=[CH:14][N:13]=1Participants
6
