Tetrahydrofuran → 4-chloro-5-iodo-7-(2-methylperhydrocyclopenta[c]pyrrol-5-yl)-7H-pyrrolo[2,3-d]pyrimidine

HRID 211230

Reaction equation

HRID 211230 reaction equation
[CH3:12][N:13]1[CH2:14][CH:15]2[CH:16]([CH2:17]1)[CH2:18][CH:19]([OH:21])[CH2:20]2.[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[nH:8][cH:9][c:10]2[I:11].[O:41]1[CH2:42][CH2:43][CH2:44][CH2:45]1.[c:22]1([P:23]([c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[cH:36][cH:37][cH:38][cH:39][cH:40]1>>[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[n:8]([CH:19]1[CH2:18][CH:16]3[CH:15]([CH2:14][N:13]([CH3:12])[CH2:17]3)[CH2:20]1)[cH:9][c:10]2[I:11]

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 11776TriphenylphosphineHCID 148092816-Chloro-7-iodo-7-deazapurineHCID 227363385-Hydroxy-2-methyloctahydrocyclopenta[c]pyrrole

Product 1

HCID 227363754-chloro-5-iodo-7-(2-methylperhydrocyclopenta[c]pyrrol-5-yl)-7H-pyrrolo[2,3-d]pyrimidine

Sources & evidence

ORD record
ord-ec979d7b529c436bbeebf14f7d340603
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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