Chloride → Ethyl 3-(1-tert-butoxycarbonylaminocyclopropyl)propiolate

HRID 211324

Reaction equation

HRID 211324 reaction equation
[C:14]([CH3:15])([CH3:16])([CH3:17])[O:18][C:19](=[O:20])[NH:21][C:22]1([CH:25]=[O:26])[CH2:23][CH2:24]1.[CH2:27]([Li:28])[CH2:29][CH2:30][CH3:31].[CH3:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13].[Cl-:1].[Cl-:39].[Cl:2][CH2:3][P+:4]([CH3:5])([CH3:6])[CH3:7].[Cl:32][C:33](=[O:34])[O:35][CH2:36][CH3:37].[Na+:38].[O:40]1[CH2:41][CH2:42][CH2:43][CH2:44]1>>[C:8](#[C:25][C:22]1([NH:21][C:19]([O:18][C:14]([CH3:15])([CH3:16])[CH3:17])=[O:20])[CH2:23][CH2:24]1)[C:33](=[O:34])[O:35][CH2:36][CH3:37]

Participants

9

Reactant 8

HCID 312Chloride2×HCID 923Sodium ionHCID 8028TetrahydrofuranHCID 8058HexaneHCID 10928Ethyl chloroformateHCID 10352385(1-Formylcyclopropyl)carbamic acid tert-butyl esterHCID 12983629Chloromethyl(trimethyl)phosphaniumHCID 178418339Butyllithium

Product 1

HCID 21261039Ethyl 3-(1-tert-butoxycarbonylaminocyclopropyl)propiolate

Sources & evidence

ORD record
ord-2f2e1524005545a7ad674eafb6f0b020
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

Loading…