Trifluoroacetic acid → 4'-bromo-2,3-dihydrospiro[furo[2,3-g][1,4]benzodioxine-8,3'-indol]-2'(1'H)-one

HRID 2122437

Reaction equation

HRID 2122437 reaction equation
[Br:1][c:2]1[c:3]2[c:4]([cH:5][cH:6][cH:7]1)[N:8]([CH:24]([c:25]1[cH:26][cH:27][cH:28][cH:29][cH:30]1)[c:31]1[cH:32][cH:33][cH:34][cH:35][cH:36]1)[C:9](=[O:23])[C:10]21[CH2:11][O:12][c:13]2[cH:14][c:15]3[c:16]([cH:21][c:22]21)[O:17][CH2:18][CH2:19][O:20]3.[CH2:37]([SiH:38]([CH2:39][CH3:40])[CH2:41][CH3:42])[CH3:43].[OH:44][C:45]([C:46]([F:47])([F:48])[F:49])=[O:50]>>[Br:1][c:2]1[c:3]2[c:4]([cH:5][cH:6][cH:7]1)[NH:8][C:9](=[O:23])[C:10]21[CH2:11][O:12][c:13]2[cH:14][c:15]3[c:16]([cH:21][c:22]21)[O:17][CH2:18][CH2:19][O:20]3

Participants

4

Reactant 3

HCID 6422Trifluoroacetic acidHCID 12052TriethylsilaneHCID 593525274'-bromo-1'-(diphenylmethyl)-2,3-dihydrospiro[furo[2,3-g][1,4]benzodioxine-8,3'-indol]-2'(1'H)-one

Product 1

HCID 593522894'-bromo-2,3-dihydrospiro[furo[2,3-g][1,4]benzodioxine-8,3'-indol]-2'(1'H)-one

Sources & evidence

ORD record
ord-df99a6d178c84b03bf6de9379550ef17
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Linked notes

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