Acetonitrile → 4-Phenyl-5-trimethylsilanylethynyl-thiazol-2-ylamine

Reaction equation

[C:21](#[CH:22])[Si:23]([CH3:24])([CH3:25])[CH3:26].[CH3:14][CH2:15][N:16]([CH2:17][CH3:18])[CH2:19][CH3:20].[CH3:27][C:28]#[N:29].[I:1][c:2]1[c:3](-[c:8]2[cH:9][cH:10][cH:11][cH:12][cH:13]2)[n:4][c:5]([NH2:7])[s:6]1>>[c:2]1([C:22]#[C:21][Si:23]([CH3:24])([CH3:25])[CH3:26])[c:3](-[c:8]2[cH:9][cH:10][cH:11][cH:12][cH:13]2)[n:4][c:5]([NH2:7])[s:6]1

Participants

Reactant 4

HCID 6342Acetonitrile

HCID 8471Triethylamine

HCID 66111Trimethylsilylacetylene

HCID 866309575-Iodo-4-phenyl-thiazol-2-ylamine

Product 1

HCID 866309584-Phenyl-5-trimethylsilanylethynyl-thiazol-2-ylamine

Sources & evidence

ORD record: ord-c0447cc47c1c44fa8083333206bbd2a1
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

Reaction notes

Loading…