Hydrochloric Acid → 4-Hydroxy-4-(4-(4-methoxyphenyl)-5-(p-tolyl)thiazol-2-yl)cyclohexan-1-one

HRID 2126395

Reaction equation

HRID 2126395 reaction equation
[C:32](=[O:33])([O-:34])[OH:35].[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6](-[c:9]2[n:10][c:11]([C:21]3([OH:31])[CH2:22][CH2:23][C:24]4([O:25][CH2:28][CH2:27][O:26]4)[CH2:29][CH2:30]3)[s:12][c:13]2-[c:14]2[cH:15][cH:16][c:17]([CH3:20])[cH:18][cH:19]2)[cH:7][cH:8]1.[ClH:42].[Na+:36].[O:37]1[CH2:38][CH2:39][CH2:40][CH2:41]1>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6](-[c:9]2[n:10][c:11]([C:21]3([OH:31])[CH2:22][CH2:23][C:24](=[O:25])[CH2:29][CH2:30]3)[s:12][c:13]2-[c:14]2[cH:15][cH:16][c:17]([CH3:20])[cH:18][cH:19]2)[cH:7][cH:8]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 769Bicarbonate IonHCID 923Sodium ionHCID 8028TetrahydrofuranHCID 672964248-(4-(4-Methoxyphenyl)-5-(p-tolyl)thiazol-2-yl)-1,4-dioxaspiro[4.5]decan-8-ol

Product 1

HCID 534757884-Hydroxy-4-(4-(4-methoxyphenyl)-5-(p-tolyl)thiazol-2-yl)cyclohexan-1-one

Sources & evidence

ORD record
ord-d79d0b03ec06456dadb376ed104bf969
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Linked notes

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