1,1-Dichloroethane → 2-(Trimethylsilyl)ethyl 3-bromo-2-thiophenecarboxylate

HRID 213378

Reaction equation

HRID 213378 reaction equation
[Br:1][c:2]1[c:3]([C:7](=[O:8])[OH:9])[s:4][cH:5][cH:6]1.[CH3:14][CH2:15][N:16]([CH2:17][CH3:18])[CH2:19][CH3:20].[CH3:21][Si:22]([CH2:23][CH2:24][OH:25])([CH3:26])[CH3:27].[Cl:28][CH:29]([Cl:30])[CH3:31].[S:10]([Cl:11])([Cl:12])=[O:13]>>[Br:1][c:2]1[c:3]([C:7](=[O:8])[O:9][CH2:24][CH2:23][Si:22]([CH3:21])([CH3:26])[CH3:27])[s:4][cH:5][cH:6]1

Participants

6

Reactant 5

HCID 63651,1-DichloroethaneHCID 8471TriethylamineHCID 180132-(Trimethylsilyl)ethanolHCID 24386Thionyl ChlorideHCID 27396883-Bromothiophene-2-carboxylic acid

Product 1

HCID 223492282-(Trimethylsilyl)ethyl 3-bromo-2-thiophenecarboxylate

Sources & evidence

ORD record
ord-809bfed6b3b641f6845da1bf880b3448
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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