Diethyl Ether → 2-(2-Iodophenyl)pyrazine

Reaction equation

[Br:1][c:2]1[c:3]([I:8])[cH:4][cH:5][cH:6][cH:7]1.[CH2:9]([Sn:10]([CH2:11][CH2:12][CH2:13][CH3:20])([c:14]1[n:15][cH:16][cH:17][n:18][cH:19]1)[CH2:21][CH2:22][CH2:23][CH3:24])[CH2:25][CH2:26][CH3:27].[CH3:28][CH2:29][O:30][CH2:31][CH3:32].[Cu:38][I:39].[O:33]1[CH2:34][CH2:35][CH2:36][CH2:37]1>>[c:2]1(-[c:14]2[n:15][cH:16][cH:17][n:18][cH:19]2)[c:3]([I:8])[cH:4][cH:5][cH:6][cH:7]1

Participants

Reactant 5

HCID 3283Diethyl Ether

HCID 8028Tetrahydrofuran

HCID 114151-Bromo-2-iodobenzene

HCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)

HCID 27373162-(Tributylstannyl)pyrazine

Product 1

HCID 689016222-(2-Iodophenyl)pyrazine

Sources & evidence

ORD record: ord-bcf0e9f24e0644418d8d44e6ee165594
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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