Sodium Ion → 6-Amino-5-ethoxycarbonylmethylthio-3-fluoropyridine-2-carboxylic acid methyl ester

Reaction equation

[CH3:10][O:11][C:12](=[O:13])[c:14]1[n:15][c:16]([NH2:22])[c:17]([Br:21])[cH:18][c:19]1[F:20].[CH3:23][CH2:24][O:25][C:26]([CH3:27])=[O:28].[H-:8].[Na+:9].[O:29]=[CH:30][N:31]([CH3:32])[CH3:33].[SH:1][CH2:2][C:3](=[O:4])[O:5][CH2:6][CH3:7]>>[S:1]([CH2:2][C:3](=[O:4])[O:5][CH2:6][CH3:7])[c:17]1[c:16]([NH2:22])[n:15][c:14]([C:12]([O:11][CH3:10])=[O:13])[c:19]([F:20])[cH:18]1

Participants

Reactant 6

HCID 923Sodium Ion

HCID 6228Dimethylformamide

HCID 8857Ethyl Acetate

HCID 12185Ethyl Thioglycolate

HCID 166653Hydride

HCID 21873678Methyl 6-amino-5-bromo-3-fluoropicolinate

Product 1

HCID 218736466-Amino-5-ethoxycarbonylmethylthio-3-fluoropyridine-2-carboxylic acid methyl ester

Sources & evidence

ORD record: ord-0df5ee246fd2485c81abfd11dd5bae7b
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

Reaction notes

Loading…