Hydrochloric Acid → Octahydropyrazino[2,1-c][1,4]thiazine 2,2-dioxide

Reaction equation

[BH3:14].[CH2:15]1[O:16][CH2:17][CH2:18][CH2:19]1.[CH2:1]1[S:2](=[O:12])(=[O:13])[CH2:3][CH2:4][N:5]2[CH:6]1[C:7](=[O:11])[NH:8][CH2:9][CH2:10]2.[CH2:21]1[O:22][CH2:23][CH2:24][CH2:25]1.[ClH:20]>>[CH2:1]1[S:2](=[O:12])(=[O:13])[CH2:3][CH2:4][N:5]2[CH:6]1[CH2:7][NH:8][CH2:9][CH2:10]2

Participants

Reactant 4

HCID 313Hydrochloric Acid

HCID 6331Borane

HCID 8028Tetrahydrofuran2×

HCID 59215885Hexahydropyrazino[2,1-c][1,4]thiazin-9(6H)-one 2,2-dioxide

Product 1

HCID 59215787Octahydropyrazino[2,1-c][1,4]thiazine 2,2-dioxide

Sources & evidence

ORD record: ord-10da36e3fc0e4184beaaceec00dc8263
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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