Tetrahydrofuran → 6-cyano-7-(4-cyanophenyl)-N-cyclopropyl-5-methyl-4-[3-(trifluoromethyl)phenyl]-7H-[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide
Reaction equation
[C:1](#[N:2])[C:3]1=[C:4]([CH3:34])[N:5]([c:24]2[cH:25][c:26]([C:30]([F:31])([F:32])[F:33])[cH:27][cH:28][cH:29]2)[c:6]2[n:7]([n:17][c:18]([S:20](=[O:21])(=[O:22])[Cl:23])[n:19]2)[CH:8]1[c:9]1[cH:10][cH:11][c:12]([C:15]#[N:16])[cH:13][cH:14]1.[CH2:46]1[O:47][CH2:48][CH2:49][CH2:50]1.[CH3:39][CH2:40][N:41]([CH2:42][CH3:43])[CH2:44][CH3:45].[CH:35]1([NH2:38])[CH2:36][CH2:37]1>>[C:1](#[N:2])[C:3]1=[C:4]([CH3:34])[N:5]([c:24]2[cH:25][c:26]([C:30]([F:31])([F:32])[F:33])[cH:27][cH:28][cH:29]2)[c:6]2[n:7]([n:17][c:18]([S:20](=[O:21])(=[O:22])[NH:38][CH:35]3[CH2:36][CH2:37]3)[n:19]2)[CH:8]1[c:9]1[cH:10][cH:11][c:12]([C:15]#[N:16])[cH:13][cH:14]1Participants
5
