Tetrahydrofuran → 4-(4-Fluoro-phenyl)-4-methyl-pentanal

Reaction equation

[Al+3:20].[CH3:1][O:2][N:3]([C:4]([CH2:5][CH2:6][C:7]([CH3:8])([CH3:9])[c:10]1[cH:11][cH:12][c:13]([F:16])[cH:14][cH:15]1)=[O:17])[CH3:18].[H-:19].[H-:22].[H-:23].[H-:24].[Li+:21].[O:25]1[CH2:26][CH2:27][CH2:28][CH2:29]1>>[CH:4]([CH2:5][CH2:6][C:7]([CH3:8])([CH3:9])[c:10]1[cH:11][cH:12][c:13]([F:16])[cH:14][cH:15]1)=[O:17]

Participants

Reactant 5

HCID 8028Tetrahydrofuran

HCID 28486Lithium ion

HCID 104727Aluminum Cation

HCID 166653Hydride4×

HCID 866385334-(4-Fluoro-phenyl)-4-methyl-pentanoic acid methoxy-methyl-amide

Product 1

HCID 866385344-(4-Fluoro-phenyl)-4-methyl-pentanal

Sources & evidence

ORD record: ord-aa8e387ce4fd4c47a5f10a78a18f02af
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

Reaction notes

Loading…