Methanol → 6-(4-Chloro-5-trifluoromethyl-pyrimidin-2-ylamino)-1,3-dihydro-indol-2-one

HRID 213751

Reaction equation

HRID 213751 reaction equation
[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH3:24][CH2:25][N:26]([CH2:27][CH3:28])[CH2:29][CH3:30].[CH3:31][OH:32].[Cl:1][c:2]1[n:3][cH:4][c:5]([C:9]([F:10])([F:11])[F:12])[c:6]([Cl:8])[n:7]1.[NH2:13][c:14]1[cH:15][cH:16][c:17]2[c:21]([cH:22]1)[NH:20][C:19](=[O:23])[CH2:18]2>>[c:2]1([NH:13][c:14]2[cH:15][cH:16][c:17]3[c:21]([cH:22]2)[NH:20][C:19](=[O:23])[CH2:18]3)[n:3][cH:4][c:5]([C:9]([F:10])([F:11])[F:12])[c:6]([Cl:8])[n:7]1

Participants

6

Reactant 5

HCID 887MethanolHCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 5905386-Amino-1,3-dihydro-2H-indol-2-oneHCID 27827742,4-Dichloro-5-(trifluoromethyl)pyrimidine

Product 1

HCID 218686976-(4-Chloro-5-trifluoromethyl-pyrimidin-2-ylamino)-1,3-dihydro-indol-2-one

Sources & evidence

ORD record
ord-3800dc6cef3e4754afaaf88adc624f9e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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