Tetrahydrofuran → t-Butyl (2-{4-[3-(4-tolyl-sulfonylamino)-propenyl]-benzoylamino}-phenyl)-carbamate

HRID 213862

Reaction equation

HRID 213862 reaction equation
[C:1]([O:2][C:3]([CH3:4])([CH3:5])[CH3:6])(=[O:7])[NH:8][S:9](=[O:10])(=[O:11])[c:12]1[cH:13][cH:14][c:15]([CH3:18])[cH:16][cH:17]1.[CH2:77]1[O:78][CH2:79][CH2:80][CH2:81]1.[O:65]=[C:66]([O:67][CH2:68][CH3:69])[N:70]=[N:71][C:72]([O:73][CH2:74][CH3:75])=[O:76].[OH:38][CH2:39][CH:40]=[CH:41][c:42]1[cH:43][cH:44][c:45]([C:46](=[O:47])[NH:48][c:49]2[c:50]([NH:55][C:56]([O:57][C:58]([CH3:59])([CH3:60])[CH3:61])=[O:62])[cH:51][cH:52][cH:53][cH:54]2)[cH:63][cH:64]1.[c:19]1([P:20]([c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[cH:33][cH:34][cH:35][cH:36][cH:37]1>>[CH2:1]([NH:8][S:9](=[O:10])(=[O:11])[c:12]1[cH:13][cH:14][c:15]([CH3:18])[cH:16][cH:17]1)[CH:40]=[CH:41][c:42]1[cH:43][cH:44][c:45]([C:46](=[O:47])[NH:48][c:49]2[c:50]([NH:55][C:56]([O:57][C:58]([CH3:59])([CH3:60])[CH3:61])=[O:62])[cH:51][cH:52][cH:53][cH:54]2)[cH:63][cH:64]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 11776TriphenylphosphineHCID 220568ethyl N-ethoxycarbonyliminocarbamateHCID 688170N-Boc-p-toluenesulfonamideHCID 72479808t-Butyl {2-[4-(3-hydroxy-propenyl)-benzoylamino]-phenyl}-carbamate

Product 1

HCID 86602774t-Butyl (2-{4-[3-(4-tolyl-sulfonylamino)-propenyl]-benzoylamino}-phenyl)-carbamate

Sources & evidence

ORD record
ord-a1c5700937694355adffe841affa2869
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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