Potassium Cation → 5-Methyl-3-(3-phenoxyazetidin-1-yl)pyrazin-2-amine

HRID 213953Notes

Reaction equation

HRID 213953 reaction equation
[Br:18][c:19]1[c:20]([NH2:26])[n:21][cH:22][c:23]([CH3:25])[n:24]1.[C:1](=[O:2])([O-:3])[O-:4].[CH3:33][CH2:34][O:35][C:36]([CH3:37])=[O:38].[K+:5].[K+:6].[O:28]=[CH:29][N:30]([CH3:31])[CH3:32].[O:7]([c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1)[CH:14]1[CH2:15][NH:16][CH2:17]1.[OH2:27]>>[O:7]([c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1)[CH:14]1[CH2:15][N:16]([c:19]2[c:20]([NH2:26])[n:21][cH:22][c:23]([CH3:25])[n:24]2)[CH2:17]1

Participants

8

Reactant 7

HCID 813Potassium Cation2×HCID 962WaterHCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 98990432-Amino-3-bromo-5-methylpyrazineHCID 128125013-Phenoxyazetidine

Product 1

HCID 682809345-Methyl-3-(3-phenoxyazetidin-1-yl)pyrazin-2-amine

Sources & evidence

ORD record
ord-6f71a7c565894f87bb4f51c69745e995
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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