Dimethyl Sulfoxide → 2-(4-((2-Amino-4-chloro-6-methylpyrimidin-5-yl)methyl)-3-fluorophenyl)acetonitrile
Reaction equation
[CH3:23][S:24]([CH3:25])=[O:26].[CH3:32][CH2:33][O:34][C:35]([CH3:36])=[O:37].[Cl:4][c:5]1[n:6][c:7]([NH2:22])[n:8][c:9]([CH3:21])[c:10]1[CH2:11][c:12]1[c:13]([F:20])[cH:14][c:15]([CH2:18][Cl:19])[cH:16][cH:17]1.[K:1][C:2]#[N:3].[O:27]=[CH:28][N:29]([CH3:30])[CH3:31]>>[C:2](#[N:3])[CH2:18][c:15]1[cH:14][c:13]([F:20])[c:12]([CH2:11][c:10]2[c:5]([Cl:4])[n:6][c:7]([NH2:22])[n:8][c:9]2[CH3:21])[cH:17][cH:16]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-cbe0b847ddfe463c8f38fa6c506af3d0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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