Tetrahydrofuran → (4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidin-5-yl)methanol
Reaction equation
[Al+3:2].[CH3:7][S:8][c:9]1[n:10][cH:11][c:12]([C:26](=[O:27])[O:28][CH2:29][CH3:30])[c:13]([NH:15][CH2:16][c:17]2[cH:18][c:19]([Cl:25])[c:20]([O:23][CH3:24])[cH:21][cH:22]2)[n:14]1.[H-:1].[H-:4].[H-:5].[H-:6].[Li+:3].[O:31]1[CH2:32][CH2:33][CH2:34][CH2:35]1>>[CH3:7][S:8][c:9]1[n:10][cH:11][c:12]([CH2:26][OH:27])[c:13]([NH:15][CH2:16][c:17]2[cH:18][c:19]([Cl:25])[c:20]([O:23][CH3:24])[cH:21][cH:22]2)[n:14]1Participants
6
Sources & evidence
- ORD record
- ord-150886f99c6d46289059b63aabfd4c5e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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