Potassium Cation → 2-{4-[(1-Cyclobutylpiperidin-4-yl)oxy]phenyl}-7-(2-fluoroethyl)-3-methyl-3,7-dihydropyrido[3,4-d]pyrimidine-4,8-dione

HRID 214869

Reaction equation

HRID 214869 reaction equation
[C:31](=[O:32])([O-:33])[O-:34].[CH3:56][CH2:57][O:58][C:59](=[O:60])[CH3:61].[CH:1]1([N:5]2[CH2:6][CH2:7][CH:8]([O:11][c:12]3[cH:13][cH:14][c:15](-[c:18]4[n:19]([CH3:30])[c:20](=[O:29])[c:21]5[c:22]([n:23]4)[c:24](=[O:28])[nH:25][cH:26][cH:27]5)[cH:16][cH:17]3)[CH2:9][CH2:10]2)[CH2:2][CH2:3][CH2:4]1.[K+:35].[K+:36].[O:37]([S:38]([c:39]1[cH:40][cH:41][c:42]([CH3:43])[cH:44][cH:45]1)(=[O:46])=[O:47])[CH2:48][CH2:49][F:50].[O:51]=[CH:52][N:53]([CH3:54])[CH3:55]>>[CH:1]1([N:5]2[CH2:6][CH2:7][CH:8]([O:11][c:12]3[cH:13][cH:14][c:15](-[c:18]4[n:19]([CH3:30])[c:20](=[O:29])[c:21]5[c:22]([n:23]4)[c:24](=[O:28])[n:25]([CH2:48][CH2:49][F:50])[cH:26][cH:27]5)[cH:16][cH:17]3)[CH2:9][CH2:10]2)[CH2:2][CH2:3][CH2:4]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 2560192-Fluoroethyl p-ToluenesulfonateHCID 672438532-{4-[(1-Cyclobutylpiperidin-4-yl)oxy]phenyl}-3-methyl-3,7-dihydropyrido[3,4-d]pyrimidine-4,8-dione

Product 1

HCID 114961612-{4-[(1-Cyclobutylpiperidin-4-yl)oxy]phenyl}-7-(2-fluoroethyl)-3-methyl-3,7-dihydropyrido[3,4-d]pyrimidine-4,8-dione

Sources & evidence

ORD record
ord-157a3f72d06646ac8af0b185a97e7d50
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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