Water → 1',2'-Dihydrospiro[cyclopentane-1,3'-indole]-2'-one

HRID 215060

Reaction equation

HRID 215060 reaction equation
[CH2:11]([CH2:12][CH2:13][CH3:14])[Li:15].[CH2:23]1[O:24][CH2:25][CH2:26][CH2:27]1.[I:16][CH2:17][CH2:18][CH2:19][CH2:20][I:21].[NH:1]1[C:2](=[O:10])[CH2:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]21.[OH2:22]>>[NH:1]1[C:2](=[O:10])[C:3]2([c:4]3[cH:5][cH:6][cH:7][cH:8][c:9]31)[CH2:11][CH2:12][CH2:13][CH2:14]2

Participants

6

Reactant 5

HCID 962WaterHCID 8028TetrahydrofuranHCID 123371,4-DiiodobutaneHCID 321710OxindoleHCID 178418339Butyllithium

Product 1

HCID 3633431',2'-Dihydrospiro[cyclopentane-1,3'-indole]-2'-one

Sources & evidence

ORD record
ord-618b4633f75b4f2c95d78f7d0cc77157
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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