Tetrahydrofuran → N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine-1-carboxamide

HRID 215337

Reaction equation

HRID 215337 reaction equation
[CH3:18][CH2:19][N:20]([CH2:21][CH3:22])[CH2:23][CH3:24].[N:25](=[C:26]=[O:27])[c:28]1[cH:29][c:30]2[c:31]([cH:36][cH:37]1)[O:32][CH2:33][CH2:34][O:35]2.[O:38]1[CH2:39][CH2:40][CH2:41][CH2:42]1.[c:1]1(-[c:7]2[n:8][s:9][c:10]([N:12]3[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]3)[n:11]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[c:7]2[n:8][s:9][c:10]([N:12]3[CH2:13][CH2:14][N:15]([C:26]([NH:25][c:28]4[cH:29][c:30]5[c:31]([cH:36][cH:37]4)[O:32][CH2:33][CH2:34][O:35]5)=[O:27])[CH2:16][CH2:17]3)[n:11]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 27761726-Isocyanato-2,3-dihydro-1,4-benzodioxineHCID 27777601-(3-Phenyl-(1,2,4)thiadiazol-5-yl)-piperazine

Product 1

HCID 68780082N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine-1-carboxamide

Sources & evidence

ORD record
ord-43c1bcc30a854aa09f3fe9e49c4a654d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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