Dichloromethane → 3-[(5-bromo-2-chloro-pyrimidin-4-yl)-(2-methylpropyl)amino]-N-methyl-propanamide

Reaction equation

[Br:1][c:2]1[c:3]([Cl:9])[n:4][c:5]([Cl:8])[n:6][cH:7]1.[CH3:10][NH:11][C:12]([CH2:13][CH2:14][NH:15][CH2:16][CH:17]([CH3:18])[CH3:19])=[O:20].[CH3:21][CH2:22][N:23]([CH2:24][CH3:25])[CH2:26][CH3:27].[Cl:28][CH2:29][Cl:30]>>[Br:1][c:2]1[c:3]([N:15]([CH2:14][CH2:13][C:12]([NH:11][CH3:10])=[O:20])[CH2:16][CH:17]([CH3:18])[CH3:19])[n:4][c:5]([Cl:8])[n:6][cH:7]1

Participants

Reactant 4

HCID 6344Dichloromethane

HCID 8471Triethylamine

HCID 2899735-Bromo-2,4-dichloropyrimidine

HCID 61870051N-methyl-3-(2-methylpropylamino)propanamide

Product 1

HCID 866175693-[(5-bromo-2-chloro-pyrimidin-4-yl)-(2-methylpropyl)amino]-N-methyl-propanamide

Sources & evidence

ORD record: ord-3573976057b4478f853b45d029ca58b4
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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