Triethylamine → 5-(4-Amino-6-chloro-pyridin-3-ylethynyl)-nicotinic acid methyl ester
Reaction equation
[CH2:24]([N:25]([CH2:26][CH3:27])[CH2:28][CH3:29])[CH3:30].[CH3:10][O:11][C:12]([c:13]1[cH:14][n:15][cH:16][c:17]([C:19]#[CH:20])[cH:18]1)=[O:21].[Cl:1][c:2]1[n:3][cH:4][c:5]([I:9])[c:6]([NH2:8])[cH:7]1.[Cu:22][I:23]>>[Cl:1][c:2]1[n:3][cH:4][c:5]([C:20]#[C:19][c:17]2[cH:16][n:15][cH:14][c:13]([C:12]([O:11][CH3:10])=[O:21])[cH:18]2)[c:6]([NH2:8])[cH:7]1Participants
5
Sources & evidence
- ORD record
- ord-241e4798b9054473bf1b133f653d424e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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