1-Azido-2-[2-(2-azidoethoxy)ethoxy]ethane → Bis-Aminoethylglycol

HRID 2184621Notes

Reaction equation

HRID 2184621 reaction equation
[N:1]([CH2:4][CH2:5][O:6][CH2:7][CH2:8][O:9][CH2:10][CH2:11][N:12]=[N+]=[N-])=[N+]=[N-]>C1COCC1.[Pt]>[NH2:1][CH2:4][CH2:5][O:6][CH2:7][CH2:8][O:9][CH2:10][CH2:11][NH2:12]

Participants

4

Reactant 1

HCID 108457051-Azido-2-[2-(2-azidoethoxy)ethoxy]ethane

Product 1

HCID 70248Bis-Aminoethylglycol

Reagents, catalysts & solvents 2

HCID 23939PlatinumCatalystHCID 8028TetrahydrofuranSolvent

Procedure

To a solution of diazide 19 (14.67 g, 0.073 mol) in THF (100 ml) 1.5 g of 5% Pt on charcoal is added. The mixture is stirred for 12 h under hydrogen. Filtration through Celite™ and evaporation of solvents at reduced pressure gives 1,8-diamino-3,6-dioxa-octane 20.

Workup

  1. filtrationFiltration
  2. customthrough Celite™ and evaporation of solvents at reduced pressure

Sources & evidence

ORD record
ord-a477a5d3ee1340b9ac5c6b429b66c7c0
Source dataset
uspto-grants-2002_06
Patent number
US06399071B1

Reaction notes

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