Hydrochloric Acid → 2-Propenoic acid, 3-phenyl-

HRID 22090

Reaction equation

HRID 22090 reaction equation
O[C:2]1[CH:12]=[CH:11][C:5]([CH:6]=[CH:7][C:8]([OH:10])=[O:9])=[CH:4][CH:3]=1.C1OC1CO.Cl.[OH-].[Na+]>CS(C)=O.OCC(CO)O>[C:8]([OH:10])(=[O:9])[CH:7]=[CH:6][C:5]1[CH:4]=[CH:3][CH:2]=[CH:12][CH:11]=1

Participants

7

Reactant 4

HCID 313Hydrochloric AcidHCID 3224-Coumaric acidHCID 11164GlycidolHCID 14798Sodium Hydroxide

Product 1

HCID 87842-Propenoic acid, 3-phenyl-

Reagents, catalysts & solvents 2

HCID 679Dimethyl SulfoxideSolventHCID 753GlycerolSolvent

Conditions

Temperature
90 °C

Procedure

1.74 g of p-hydroxy cinnamic acid and 4.0 g of glycidol were dissolved in 2 ml of DMSO, and catalytic amount of hydrochloric acid was added. The solution was heated to 90° C., heating and agitation were carried out for 1 hour, neutralized by adding sodium hydroxide and then the adduct of cinnamic acid and glycerin was obtained.

Workup

  1. temperatureheating

Sources & evidence

ORD record
ord-aa165162a2e042ea8030a1f87d6b5d99
Source dataset
uspto-grants-1995_06
Patent number
US05426210

Linked notes

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