Arachidonic Acid → 5,8,11,14-Eicosatetraenoic acid, sodium salt, (all-Z)-

HRID 224667

Reaction equation

HRID 224667 reaction equation
[C:1]([OH:22])(=[O:21])[CH2:2][CH2:3][CH2:4]/[CH:5]=[CH:6]\[CH2:7]/[CH:8]=[CH:9]\[CH2:10]/[CH:11]=[CH:12]\[CH2:13]/[CH:14]=[CH:15]\[CH2:16][CH2:17][CH2:18][CH2:19][CH3:20].C([O-])(O)=O.[Na+:27]>>[C:1]([O-:22])(=[O:21])[CH2:2][CH2:3][CH2:4]/[CH:5]=[CH:6]\[CH2:7]/[CH:8]=[CH:9]\[CH2:10]/[CH:11]=[CH:12]\[CH2:13]/[CH:14]=[CH:15]\[CH2:16][CH2:17][CH2:18][CH2:19][CH3:20].[Na+:27]

Participants

3

Reactant 2

HCID 444899Arachidonic AcidHCID 516892Sodium Bicarbonate

Product 1

HCID 236754535,8,11,14-Eicosatetraenoic acid, sodium salt, (all-Z)-

Procedure

Arachidonic acid (99% pure, a product of Sigma Co., Ltd.) was dissolved in 0.1 M NaHCO3, and a 3.3 mM solution of sodium arachidonate was prepared. The solution was diluted with physiological saline to a concentration of 1 mM and used in the experiments. The 3.3 mM solution was stored in a refrigerator as a stock solution, and the 1 mM solution was newly prepared from the stock solution every time it was used.

Workup

  1. additionThe solution was diluted with physiological saline to a concentration of 1 mM

Sources & evidence

ORD record
ord-389bd937a4604da6938e8ff907256d54
Source dataset
uspto-grants-1980_11
Patent number
US04233309

Linked notes

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