Methacrylic Acid → (2-Adamantyloxymethyl)methacrylate
Reaction equation
[C:1]([OH:6])(=[O:5])[C:2]([CH3:4])=[CH2:3].C(N(CC)CC)C.Cl[CH2:15][O:16][CH:17]1[CH:24]2[CH2:25][CH:20]3[CH2:21][CH:22]([CH2:26][CH:18]1[CH2:19]3)[CH2:23]2>O1CCCC1>[CH:18]12[CH2:26][CH:22]3[CH2:21][CH:20]([CH2:25][CH:24]([CH2:23]3)[CH:17]1[O:16][CH2:15][O:5][C:1](=[O:6])[C:2]([CH3:4])=[CH2:3])[CH2:19]2Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
6.9 g of methacrylic acid was dissolved in 200 ml of tetrahydrofuran, and 8.0 g of triethylamine was added thereto. Then, the resultant was stirred at room temperature, and 100 ml of tetrahydrofuran having 15 g of 2-adamantyl chloromethyl ether dissolved was dropwise added.
Workup
- additionwas dropwise added
Sources & evidence
- ORD record
- ord-2145fcc7e51f47f5ba156484ec8062fd
- Source dataset
- uspto-grants-2010_12
- Patent number
- US07858286B2
Reaction notes
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