Triethylamine → HCID 22273083, compound

HRID 227375

Reaction equation

HRID 227375 reaction equation
[O:1]1[CH2:6][CH2:5][CH:4]([CH2:7][CH2:8][OH:9])[CH2:3][CH2:2]1.C(N(CC)CC)C.[CH3:17][S:18](Cl)(=[O:20])=[O:19]>O1CCCC1>[CH3:17][S:18]([O:9][CH2:8][CH2:7][CH:4]1[CH2:5][CH2:6][O:1][CH2:2][CH2:3]1)(=[O:20])=[O:19]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 177509442-(Oxan-4-yl)ethan-1-ol

Product 1

HCID 22273083HCID 22273083, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

The product of Example 8A (2.9 mmol), triethylamine (1.2 mL, 8.7 mmol) and methanesulfonyl chloride (0.34 mL, 4.4 mmol) in 10 mL tetrahydrofuran (THF) were reacted and the product isolated as in Example 1C to give the title compound that was used directly in the next reaction.

Workup

  1. customthe product isolated as in Example 1C

Sources & evidence

ORD record
ord-cab984eb0dbd4e83a9687a4e09548263
Source dataset
uspto-grants-2009_07
Patent number
US07560481B2

Linked notes

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