Ethyl pyruvate → ethyl (2S)-2-((3,5-dichlorophenyl)amino)propanoate
Reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:6]=[C:7]([Cl:9])[CH:8]=1)[NH2:5].[C:10]([O:15][CH2:16][CH3:17])(=[O:14])[C:11]([CH3:13])=O>>[CH2:16]([O:15][C:10](=[O:14])[C@H:11]([CH3:13])[NH:5][C:4]1[CH:3]=[C:2]([Cl:1])[CH:8]=[C:7]([Cl:9])[CH:6]=1)[CH3:17]Participants
3
Procedure
Following General Procedure AA above and using 3,5-dichloroaniline (Aldrich) and ethyl pyruvate (Aldrich), the title compound was prepared.
Sources & evidence
- ORD record
- ord-3b379b61c98e40aa8ee5f55ab296dda3
- Source dataset
- uspto-grants-2005_02
- Patent number
- US06849650B2
Reaction notes
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