Hydrochloric Acid → HCID 20184577, compound
Reaction equation
[CH3:1][O:2][C:3]1[CH:11]=[C:10]([S:12]([Cl:15])(=[O:14])=[O:13])[CH:9]=[CH:8][C:4]=1[C:5](O)=O.[CH3:16][NH2:17].[NH2:18][C:19]1[C:24]([NH2:25])=[CH:23][N:22]=[CH:21][N:20]=1.Cl>>[ClH:15].[CH3:1][O:2][C:3]1[CH:11]=[C:10]([S:12]([NH:17][CH3:16])(=[O:14])=[O:13])[CH:9]=[CH:8][C:4]=1[C:5]1[NH:25][C:24]2[C:19](=[N:20][CH:21]=[N:22][CH:23]=2)[N:18]=1Participants
5
Procedure
Prepared analogously to Example 50 from 2-methoxy-4-chlorosulfonyl-benzoic acid, aqueous methylamine solution, and 4,5-diamino-pyrimidine. The crude free base was converted into the hydrochloride with 2N hydrochloride acid, and the hydrochloride was purified by boiling with methanol.