Tetrahydrofuran → Methyl 2-(bromomethyl)-2'-fluoro-5'-(methyloxy)-1,1'-biphenyl-4-carboxylate
Reaction equation
[Br:41][N:42]1[C:43](=[O:44])[CH2:45][CH2:46][C:47]1=[O:48].[CH2:49]1[O:50][CH2:51][CH2:52][CH2:53]1.[F:1][c:2]1[c:3](-[c:10]2[c:11]([CH2:20][OH:21])[cH:12][c:13]([C:16](=[O:17])[O:18][CH3:19])[cH:14][cH:15]2)[cH:4][c:5]([O:8][CH3:9])[cH:6][cH:7]1.[c:22]1([P:23]([c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[cH:36][cH:37][cH:38][cH:39][cH:40]1>>[F:1][c:2]1[c:3](-[c:10]2[c:11]([CH2:20][Br:41])[cH:12][c:13]([C:16](=[O:17])[O:18][CH3:19])[cH:14][cH:15]2)[cH:4][c:5]([O:8][CH3:9])[cH:6][cH:7]1Participants
5
