Ammonium → 2-(2,3-dihydro-6-methyl-4-oxo-5-phenyl-4H-1,3-oxazin-3-yl)-2,4-dimethylpentan-3-ol

Reaction equation

[CH3:6][C:7]1=[C:8]([c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[C:9](=[O:18])[N:10]([C:13]([CH:14]=[O:15])([CH3:16])[CH3:17])[CH2:11][O:12]1.[CH:2]([CH3:3])([CH3:4])[Mg+:5].[Cl-:1].[Cl-:25].[NH4+:26].[O:27]1[CH2:28][CH2:29][CH2:30][CH2:31]1>>[CH:2]([CH3:3])([CH3:4])[CH:14]([C:13]([N:10]1[C:9](=[O:18])[C:8]([c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)=[C:7]([CH3:6])[O:12][CH2:11]1)([CH3:16])[CH3:17])[OH:15]

Participants

Reactant 5

HCID 223Ammonium

HCID 312Chloride2×

HCID 8028Tetrahydrofuran

HCID 221182842-(2,3-dihydro-6-methyl-4-oxo-5-phenyl-4H-1,3-oxazin-3-yl)-2-methylpropionaldehyde

HCID 178461726HCID 178461726, compound

Product 1

HCID 187955302-(2,3-dihydro-6-methyl-4-oxo-5-phenyl-4H-1,3-oxazin-3-yl)-2,4-dimethylpentan-3-ol

Sources & evidence

ORD record: ord-dcf3aee431514a4195e28cd893c970b3
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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