Dimethyl Sulfoxide → 2-(2-Methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-3-yl)acetaldehyde

Reaction equation

[CH2:33]([Cl:34])[Cl:35].[CH3:26][CH2:27][N:28]([CH2:29][CH3:30])[CH2:31][CH3:32].[CH3:7][S:8](=[O:9])[CH3:10].[Cl:1][C:2]([C:3]([Cl:4])=[O:5])=[O:6].[OH2:36].[OH:11][CH2:12][CH2:13][c:14]1[c:15]([CH3:25])[n:16][c:17]2[n:18]([c:19]1=[O:20])[CH2:21][CH2:22][CH2:23][CH2:24]2>>[O:11]=[CH:12][CH2:13][c:14]1[c:15]([CH3:25])[n:16][c:17]2[n:18]([c:19]1=[O:20])[CH2:21][CH2:22][CH2:23][CH2:24]2

Participants

Reactant 6

HCID 679Dimethyl Sulfoxide

HCID 962Water

HCID 6344Dichloromethane

HCID 8471Triethylamine

HCID 65578Oxalyl chloride

HCID 114131273-(2-hydroxyethyl)-2-methyl-4H,6H,7H,8H,9H-pyrido(1,2-a)pyrimidin-4-one

Product 1

HCID 102144672-(2-Methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-3-yl)acetaldehyde

Sources & evidence

ORD record: ord-a1bd32713c1b4017b6ea75e80dcc338d
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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