2,2,2-Trifluoroethanol → 2-Amino-4-chloromethyl-6-(2,2,2-trifluoroethoxy)pyrimidine

HRID 2318944

Reaction equation

HRID 2318944 reaction equation
[NH2:2][c:3]1[n:4][c:5]([CH2:10][Cl:11])[cH:6][c:7]([Cl:9])[n:8]1.[Na:1].[OH:12][CH2:13][C:14]([F:15])([F:16])[F:17]>>[NH2:2][c:3]1[n:4][c:5]([CH2:10][Cl:11])[cH:6][c:7]([O:12][CH2:13][C:14]([F:15])([F:16])[F:17])[n:8]1

Participants

4

Reactant 3

HCID 64092,2,2-TrifluoroethanolHCID 5360545SodiumHCID 201534884-Chloro-6-(chloromethyl)pyrimidin-2-amine

Product 1

HCID 201534932-Amino-4-chloromethyl-6-(2,2,2-trifluoroethoxy)pyrimidine

Sources & evidence

ORD record
ord-8c68ad6de2ea4ac98fbd5dc46ff4307d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Linked notes

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