Dimethylformamide → Benzyl 2-(2-chloro-2-oxoethyl)pyrrolidine-1-carboxylate

Reaction equation

[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH:12]([CH2:16][C:17](=[O:18])[OH:19])[CH2:13][CH2:14][CH2:15]1.[Cl:20][CH2:21][Cl:22].[Cl:23][C:24]([C:25]([Cl:26])=[O:27])=[O:28].[O:29]=[CH:30][N:31]([CH3:32])[CH3:33]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH:12]([CH2:16][C:17](=[O:19])[Cl:20])[CH2:13][CH2:14][CH2:15]1

Participants

Reactant 4

HCID 6228Dimethylformamide

HCID 6344Dichloromethane

HCID 65578Oxalyl chloride

HCID 12870024{1-[(Benzyloxy)carbonyl]pyrrolidin-2-yl}acetic acid

Product 1

HCID 57474470Benzyl 2-(2-chloro-2-oxoethyl)pyrrolidine-1-carboxylate

Sources & evidence

ORD record: ord-17a12b13a94a48bda54aff5305b247c4
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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