Ammonium → Tert-butyl 5-formyl-1,2,3,4-tetrahydroisoquinoline-2-carboxylate

HRID 2328653

Reaction equation

HRID 2328653 reaction equation
[C:19]([Li:20])([CH3:21])([CH3:22])[CH3:23].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][cH:12][cH:13][c:14]([Br:18])[c:15]2[CH2:16][CH2:17]1.[CH3:34][CH2:35][O:36][CH2:37][CH3:38].[CH:24](=[O:25])[N:26]1[CH2:27][CH2:28][O:29][CH2:30][CH2:31]1.[Cl-:32].[NH4+:33]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][cH:12][cH:13][c:14]([CH:24]=[O:25])[c:15]2[CH2:16][CH2:17]1

Participants

7

Reactant 6

HCID 223AmmoniumHCID 312ChlorideHCID 3283Diethyl EtherHCID 20417N-FormylmorpholineHCID 18315369tert-Butyl 5-bromo-3,4-dihydroisoquinoline-2(1H)-carboxylateHCID 178418306HCID 178418306, compound

Product 1

HCID 22335239Tert-butyl 5-formyl-1,2,3,4-tetrahydroisoquinoline-2-carboxylate

Sources & evidence

ORD record
ord-0c4e891cd9e248eca636f3e88b187ae1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Linked notes

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