Water → 4-(2-Oxoethyl)-piperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester

Reaction equation

[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[C:6]1([CH2:19][CH:20]=[CH2:21])[CH2:7][CH2:8][N:9]([C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:10][CH2:11]1.[CH3:22][CH2:23][O:24][C:25]([CH3:26])=[O:27].[CH:28]([OH:29])([CH3:30])[CH3:31].[O:33]=[Os:34](=[O:35])(=[O:36])=[O:37].[OH2:32]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[C:6]1([CH2:19][CH:20]=[O:24])[CH2:7][CH2:8][N:9]([C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:10][CH2:11]1

Participants

Reactant 5

HCID 962Water

HCID 3776Isopropanol

HCID 8857Ethyl Acetate

HCID 30318Osmium Tetroxide

HCID 162182701-tert-Butyl 4-ethyl 4-(prop-2-en-1-yl)piperidine-1,4-dicarboxylate

Product 1

HCID 584784234-(2-Oxoethyl)-piperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester

Sources & evidence

ORD record: ord-41c3113392264892b3c4e020ed6cdbb5
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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