Thiophenol → (4-Bromo-6-phenylsulphanylpyrimidin-2-yl)-methylamine

Reaction equation

[Br:1][c:2]1[n:3][c:4]([NH:9][CH3:10])[n:5][c:6]([Br:8])[cH:7]1.[CH3:19][N:20]1[CH2:21][CH2:22][CH2:23][C:24]1=[O:25].[Na:11].[c:12]1([SH:18])[cH:13][cH:14][cH:15][cH:16][cH:17]1>>[Br:1][c:2]1[n:3][c:4]([NH:9][CH3:10])[n:5][c:6]([S:18][c:12]2[cH:13][cH:14][cH:15][cH:16][cH:17]2)[cH:7]1

Participants

Reactant 4

HCID 7969Thiophenol

HCID 13387N-methyl-2-pyrrolidone

HCID 5360545Sodium

HCID 19605496(4,6-Dibromopyrimidin-2-yl)-methylamine

Product 1

HCID 19605540(4-Bromo-6-phenylsulphanylpyrimidin-2-yl)-methylamine

Sources & evidence

ORD record: ord-ee82bc9705a34a5a8aab87d5a9d2caf0
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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