Dimethylformamide → N-(1-benzyloxycarbonylcyclopentyl)-N-(2'-cyanobiphenyl-4-ylmethyl)-amine

HRID 2335580

Reaction equation

HRID 2335580 reaction equation
[Br:1][CH2:2][c:3]1[cH:4][cH:5][c:6](-[c:9]2[c:10]([C:15]#[N:16])[cH:11][cH:12][cH:13][cH:14]2)[cH:7][cH:8]1.[CH2:17]([c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1)[O:24][C:25](=[O:26])[C:27]1([NH2:32])[CH2:28][CH2:29][CH2:30][CH2:31]1.[CH3:42][N:43]([CH3:44])[CH:45]=[O:46].[CH:33]([N:34]([CH:35]([CH3:36])[CH3:37])[CH2:38][CH3:39])([CH3:40])[CH3:41]>>[CH2:2]([c:3]1[cH:4][cH:5][c:6](-[c:9]2[c:10]([C:15]#[N:16])[cH:11][cH:12][cH:13][cH:14]2)[cH:7][cH:8]1)[NH:32][C:27]1([C:25]([O:24][CH2:17][c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)=[O:26])[CH2:28][CH2:29][CH2:30][CH2:31]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 81531DiisopropylethylamineHCID 231228Benzyl 1-aminocyclopentane-1-carboxylateHCID 15019124'-(Bromomethyl)-2-cyanobiphenyl

Product 1

HCID 20083512N-(1-benzyloxycarbonylcyclopentyl)-N-(2'-cyanobiphenyl-4-ylmethyl)-amine

Sources & evidence

ORD record
ord-e41dfe094ec0491aa4819cc565b13357
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Linked notes

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