Hydroxide → (2-Chloro-4-morpholinopyrido[3,2-d]pyrimidin-6-yl)methanol

Reaction equation

[C:1](=[O:2])([CH3:3])[O:4][CH2:5][c:6]1[cH:7][cH:8][c:9]2[n:10][c:11]([Cl:22])[n:12][c:13]([N:16]3[CH2:17][CH2:18][O:19][CH2:20][CH2:21]3)[c:14]2[n:15]1.[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[Li+:23].[OH-:24].[OH2:30]>>[OH:4][CH2:5][c:6]1[cH:7][cH:8][c:9]2[n:10][c:11]([Cl:22])[n:12][c:13]([N:16]3[CH2:17][CH2:18][O:19][CH2:20][CH2:21]3)[c:14]2[n:15]1

Participants

Reactant 5

HCID 961Hydroxide

HCID 962Water

HCID 8028Tetrahydrofuran

HCID 28486Lithium ion

HCID 86657075(2-Chloro-4-morpholinopyrido[3,2-d]pyrimidin-6-yl)methyl acetate

Product 1

HCID 53488008(2-Chloro-4-morpholinopyrido[3,2-d]pyrimidin-6-yl)methanol

Sources & evidence

ORD record: ord-763c81812adf4edbbf5af7f530b5380b
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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