Tetrahydrofuran → 3-(4-bromo-5H-furan-2-ylidene)-6-fluoro-1,3-dihydro-indol-2-one

HRID 2345489

Reaction equation

HRID 2345489 reaction equation
[Br:27][C:28]1=[CH:29][C:30](=[O:33])[O:31][CH2:32]1.[CH2:22]1[O:23][CH2:24][CH2:25][CH2:26]1.[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1.[CH3:13][Si:14]([N-:15][Si:16]([CH3:17])([CH3:18])[CH3:19])([CH3:20])[CH3:21].[F:1][c:2]1[cH:3][cH:4][c:5]2[c:9]([cH:10]1)[NH:8][C:7](=[O:11])[CH2:6]2.[Li+:12]>>[F:1][c:2]1[cH:3][cH:4][c:5]2[c:9]([cH:10]1)[NH:8][C:7](=[O:11])[C:6]2=[C:30]1[CH:29]=[C:28]([Br:27])[CH2:32][O:31]1

Participants

6

Reactant 5

HCID 8028Tetrahydrofuran2×HCID 28486Lithium ionHCID 3280088Npc316347HCID 37310136-fluoro-2,3-dihydro-1H-indol-2-oneHCID 117895364-bromo-5H-furan-2-one

Product 1

HCID 694018893-(4-bromo-5H-furan-2-ylidene)-6-fluoro-1,3-dihydro-indol-2-one

Sources & evidence

ORD record
ord-7a5f5d2be97d49ee8bb0015c3a5e8912
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Linked notes

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