Tetrahydrofuran → 4-(2-Bromo-5-fluorophenoxy)piperidine-1-carbonitrile
Reaction equation
[Br:1][c:2]1[c:3]([O:4][CH:5]2[CH2:6][CH2:7][NH:8][CH2:9][CH2:10]2)[cH:11][c:12]([F:15])[cH:13][cH:14]1.[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[CH3:19][CH2:20][N:21]([CH2:22][CH3:23])[CH2:24][CH3:25].[N:16]#[C:17][Br:18]>>[Br:1][c:2]1[c:3]([O:4][CH:5]2[CH2:6][CH2:7][N:8]([C:17]#[N:16])[CH2:9][CH2:10]2)[cH:11][c:12]([F:15])[cH:13][cH:14]1Participants
5
Sources & evidence
- ORD record
- ord-2815556f1d934cb99b2bc6c1689ac6fe
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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