Bromide ion → (4-Chloro-phenyl)-[6-(6-methyl-pyridin-2-yl)-pyrazin-2-yl]-carbamic acid tert-butyl ester
Reaction equation
[Br-:1].[C:10]([CH3:11])([CH3:12])([CH3:13])[O:14][C:15]([N:16]([c:17]1[n:18][c:19]([Cl:23])[cH:20][n:21][cH:22]1)[c:24]1[cH:25][cH:26][c:27]([Cl:30])[cH:28][cH:29]1)=[O:31].[CH3:2][c:3]1[cH:4][cH:5][cH:6][c:7]([Zn+:9])[n:8]1.[O:32]1[CH2:33][CH2:34][CH2:35][CH2:36]1.[Pd:37]([Cl:38])[Cl:39].[c:40]1([P:41]([c:42]2[cH:43][cH:44][cH:45][cH:46][cH:47]2)[c:48]2[cH:49][cH:50][cH:51][cH:52][cH:53]2)[cH:54][cH:55][cH:56][cH:57][cH:58]1.[c:59]1([P:60]([c:61]2[cH:62][cH:63][cH:64][cH:65][cH:66]2)[c:67]2[cH:68][cH:69][cH:70][cH:71][cH:72]2)[cH:73][cH:74][cH:75][cH:76][cH:77]1>>[CH3:2][c:3]1[cH:4][cH:5][cH:6][c:7](-[c:19]2[n:18][c:17]([N:16]([C:15]([O:14][C:10]([CH3:11])([CH3:12])[CH3:13])=[O:31])[c:24]3[cH:25][cH:26][c:27]([Cl:30])[cH:28][cH:29]3)[cH:22][n:21][cH:20]2)[n:8]1
