Dicyclohexylcarbodiimide → 2-Dimethylaminopyridine

HRID 235218

Reaction equation

HRID 235218 reaction equation
[CH3:1][C@H]1OC(=O)C2C(O)=CC(O)=C(Cl)C=2CC(=O)C=CC=C[C@H]2O[C@H]2C1.C(O)(=O)CCCCCCCCCCCC.[CH:41]1([N:47]=[C:48]=[N:49][CH:50]2[CH2:55][CH2:54][CH2:53]CC2)CCCCC1>O1CCCC1>[CH3:1][N:47]([C:48]1[CH:53]=[CH:54][CH:55]=[CH:50][N:49]=1)[CH3:41]

Participants

5

Reactant 3

HCID 10868DicyclohexylcarbodiimideHCID 12530Tridecanoic acidHCID 11268547CID 11268547

Product 1

HCID 218852-Dimethylaminopyridine

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Following a procedure similar to that described in Example 12, but using 400 mg of radicicol, 588 mg of tridecanoic acid, 6 ml of dry tetrahydrofuran, 566 mg of dicyclohexylcarbodiimide and a catalytic amount of dimethylaminopyridine, 688 mg of the title compound were obtained.

Sources & evidence

ORD record
ord-ed78305552ee4386b4d971d05ee4d43c
Source dataset
uspto-grants-1997_01
Patent number
US05597846

Linked notes

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