Diethyl Pyrocarbonate → (R)-3-(4-tert-Butylphenyl)-N-[1-(3-fluoro-4-methanesulfonylamino-5-vinylphenyl)ethyl]acrylamide

Reaction equation

[NH2:1][CH:2]([C:4]1[CH:9]=[C:8]([CH:10]=[CH2:11])[C:7]([NH:12][S:13]([CH3:16])(=[O:15])=[O:14])=[C:6]([F:17])[CH:5]=1)[CH3:3].[C:18]([C:22]1[CH:27]=[CH:26][C:25]([CH:28]=[CH:29][C:30](O)=[O:31])=[C:24](NCCC(C)C)[CH:23]=1)([CH3:21])([CH3:20])[CH3:19].CCOC(OC(OCC)=O)=O>CN(C=O)C>[C:18]([C:22]1[CH:23]=[CH:24][C:25]([CH:28]=[CH:29][C:30]([NH:1][C@@H:2]([C:4]2[CH:9]=[C:8]([CH:10]=[CH2:11])[C:7]([NH:12][S:13]([CH3:16])(=[O:15])=[O:14])=[C:6]([F:17])[CH:5]=2)[CH3:3])=[O:31])=[CH:26][CH:27]=1)([CH3:21])([CH3:19])[CH3:20]