Allylamine → N-allyl-3-(N-vinylformamido)propionamide
Reaction equation
[CH:1]([N:3]([CH2:6][CH2:7][C:8]([O:10]CC)=O)[CH:4]=[O:5])=[CH2:2].[CH2:13]([NH2:16])[CH:14]=[CH2:15].C[O-].[Na+]>CO>[CH2:13]([NH:16][C:8](=[O:10])[CH2:7][CH2:6][N:3]([CH:1]=[CH2:2])[CH:4]=[O:5])[CH:14]=[CH2:15]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 90 °C
Procedure
A 100mL stainless steel high pressure reactor was charged with 17.1 grams (0.1 mol) of ethyl 3-(N-vinylformamido)propionate, 5.7 grams (0.1 mol) of allylamine and 0.15 gram of 25% sodium methoxide in methanol solution. The mixture was heated at 90° C. for 3 hours. Subsequent NMR analysis of the reaction mixture showed no conversion of the starting materials.
Sources & evidence
- ORD record
- ord-e627c68d0c1743fc987ec32e90fb2b64
- Source dataset
- uspto-grants-1998_03
- Patent number
- US05728878
Reaction notes
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