Itaconic acid → HCID 86658305, compound
Reaction equation
[C:1]([OH:9])(=[O:8])[C:2]([CH2:4][C:5]([OH:7])=[O:6])=[CH2:3].CN.C(C1C[N:18](C)[C:17](=O)C1)(O)=O>O>[C:1]([OH:9])(=[O:8])[C:2]([CH2:4][C:5]([OH:7])=[O:6])=[CH2:3].[CH3:17][NH2:18]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
Itaconic acid (18.5 g; 0.142 mol) and methylamine (41% in water, 10.7 g based on the aqueous solution, 0.142 mol, 1.0 equivalent) were mixed as in example 8. In addition, the addition of 20 ml of water was required in order to prevent formation of precipitate at 50° C. NMR analysis showed that the itaconic acid:4-carboxy-1-methylpyrrolidone ratio was 100:0.
Workup
- additionwere mixed as in example 8
- customat 50° C
Sources & evidence
- ORD record
- ord-d0e5462f54974f2081f053ca425e874c
- Source dataset
- uspto-grants-2014_08
- Patent number
- US08796472B2
Reaction notes
Loading…