Hydrochloric Acid → Methane

HRID 2412822

Reaction equation

HRID 2412822 reaction equation
Cl.[CH3:2][N:3]([CH3:12])[C:4]1[CH:11]=[CH:10][C:7]([CH:8]=O)=[CH:6][CH:5]=1.[C:13]1(C)[CH:18]=[CH:17][C:16]([S:19]([O-:21])=[O:20])=[CH:15][CH:14]=1.[Na+].[CH2:24]([N:26]1[C:34]2[C:29](=[CH:30][CH:31]=[CH:32][CH:33]=2)[CH:28]=[C:27]1[CH3:35])[CH3:25].[CH2:36](O)C>>[CH4:2].[CH3:2][N:3]([CH3:12])[C:4]1[CH:11]=[CH:10][C:7]([C:8]2[C:17]([C:28]3[C:29]4[C:34](=[CH:33][CH:32]=[CH:31][CH:30]=4)[N:26]([CH2:24][CH3:25])[C:27]=3[CH3:35])=[C:16]([S:19]([CH3:36])(=[O:21])=[O:20])[CH:15]=[CH:14][C:13]=2[CH3:18])=[CH:6][CH:5]=1

Participants

7

Reactant 5

HCID 313Hydrochloric AcidHCID 702EthanolHCID 74794-(Dimethylamino)BenzaldehydeHCID 1704321H-Indole, 1-ethyl-2-methyl-HCID 2723791Sodium p-toluenesulfinate

Product 2

HCID 297MethaneHCID 20184815[(4-Dimethylaminophenyl)(1-ethyl-2-methyl-3-indolyl)(4-methylphenylsulfonyl)]methane

Procedure

Proceeding in a manner similar to that described in Example 1 above substituting for ethyl alcohol and the concentrated hydrochloric acid the appropriate reaction medium and the appropriate catalyst listed in Examples 58-82 of Table A hereinbelow, 4-dimethylaminobenzaldehyde, sodium p-toluenesulfinate and 1-ethyl-2-methylindole were interacted at the indicated temperature to obtain a methane of Formula II wherein R=4--CH3 ; R1 =CH3 ; R3 =R5 =H; R6 =N(CH3)2. A toluene or acetone solution of the product from Examples 58-82 contacted with silica gel developed at blue-red colored image.

Sources & evidence

ORD record
ord-9844834c967443a9a82115fbb841dac2
Source dataset
uspto-grants-1985_01
Patent number
US04494989

Linked notes

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